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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3B All Species: 24.55
Human Site: Y602 Identified Species: 41.54
UniProt: Q7Z3V4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3V4 NP_569733.2 1068 123070 Y602 H G W L M V L Y E R D C R R R
Chimpanzee Pan troglodytes XP_509354 1068 122921 Y602 H G W L M V L Y E R D C R R R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543437 1068 123121 Y602 H G W L M V L Y E R D C R R R
Cat Felis silvestris
Mouse Mus musculus Q9ES34 1070 122743 Y604 H G W L M V L Y E R D C R R R
Rat Rattus norvegicus NP_001137366 1070 122598 Y604 H G W L M V L Y E R D C R R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423951 837 96057 I417 L Q Y I P H V I P H K N R V L
Frog Xenopus laevis Q6DCL5 944 106566 L522 V C K H D E V L K C F V T R N
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 S345 L N P S P N G S R A A V E A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 Q571 R A S P M P N Q T R R V E D D
Honey Bee Apis mellifera XP_392283 1063 121439 Y598 H T L L M A I Y R R D C R R T
Nematode Worm Caenorhab. elegans NP_499392 1066 120863 Y604 H S L L T V L Y E R D S R R S
Sea Urchin Strong. purpuratus XP_786887 582 66877 I162 I L Q K I P H I I P H R E R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 L588 M G I V V S E L L S Q L Q D W
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 K490 L L L N K M K K R L K S S L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 N.A. 96.5 N.A. 92.1 91.8 N.A. N.A. 68.6 20.8 22.8 N.A. 20.4 51.5 37.6 37.1
Protein Similarity: 100 98.9 N.A. 98.5 N.A. 96 96.1 N.A. N.A. 74 40.1 38.4 N.A. 37.1 69.1 58.4 44.9
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 6.6 6.6 0 N.A. 13.3 60 66.6 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 26.6 20 6.6 N.A. 13.3 66.6 66.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 28.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.7 42 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 0 0 0 8 8 0 0 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 43 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 50 0 0 15 8 % D
% Glu: 0 0 0 0 0 8 8 0 43 0 0 0 22 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 43 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 50 0 0 8 0 8 8 0 0 8 8 0 0 0 0 % H
% Ile: 8 0 8 8 8 0 8 15 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 8 0 8 8 8 0 15 0 0 0 0 % K
% Leu: 22 15 22 50 0 0 43 15 8 8 0 8 0 8 8 % L
% Met: 8 0 0 0 50 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 8 8 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 8 8 15 15 0 0 8 8 0 0 0 0 0 % P
% Gln: 0 8 8 0 0 0 0 8 0 0 8 0 8 0 8 % Q
% Arg: 8 0 0 0 0 0 0 0 22 58 8 8 58 65 43 % R
% Ser: 0 8 8 8 0 8 0 8 0 8 0 15 8 0 8 % S
% Thr: 0 8 0 0 8 0 0 0 8 0 0 0 8 0 8 % T
% Val: 8 0 0 8 8 43 15 0 0 0 0 22 0 8 8 % V
% Trp: 0 0 36 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _